The versatility of polyelectrolyte multilayers, PEMs, is high, which makes them interesting for e.g. biomedical applications. The functionality is largely determined by the layer properties, which needs to be understood to be tailored. Here, we show how PEMs can be characterized with QCM-D.
Biocompatibility, antibacterial qualities, and drug delivery can be achieved by for example polymer brushes, polyelectrolyte multilayers or hydrogels. When tailoring the interfacial properties of these thin films, the layer conformation, such as crosslinking and degree of hydration is important.
Thanks to the complementary information combinatorial QCM-D and ellipsometry can provide, these two allow one to simultaneously monitor both polymer brush swelling and deswelling behavior, as well as attachment and detachment of protein.
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