QCM-D

~ 6 min

Why are overtones important in QCM?

On the topic of QCM, the different resonance harmonics, i.e., the fundamental and the overtone harmonics, are often subject to discussion. So, what is the deal with the overtones? Are they really needed, and if they are, when and why are they important?

> 3 min

Key aspects to consider when reading a QCM specification

When you are to invest in a new QCM-system, there are several aspects of the instrument to evaluate such as price, experimental capabilities and data quality. Price is straightforward, but how about the other two factors? Here we guide you how to asses experimental capabilities and data quality.

> 4 min

The Sauerbrey equation or Viscoelastic modelling? – how to assess which method to use

You have finished a set of successful QCM experiments, and it is time to analyze the data. Mass and thickness quantification are on the to-do list, and you must decide between the Sauerbrey equation and viscoelastic modeling. Here we present guidelines on how to evaluate which method to use.

~ 4 min

Characterization of polyelectrolyte multilayer build-up and structure

The versatility of polyelectrolyte multilayers, PEMs, is high, which makes them interesting for e.g. biomedical applications. The functionality is largely determined by the layer properties, which needs to be understood to be tailored. Here, we show how PEMs can be characterized with QCM-D.

7 min

Why temperature stability is critical in QCM-measurements

Temperature stability is key to achieve reliable and reproducible QCM measurements. But why is a stable temperature so important? And how will temperature variations affect your measurements? Here we explain the causes and effects of temperature related artifacts in QCM measurements.

> 4 min

What is the Sauerbrey equation?

In the context of QCM technology, there is often a reference to the so-called Sauerbrey equation. Here we explain what this equation is, and when it should be used.

3 min

What is dissipation?

Talking about QCM-based instrumentation, one often comes across the concepts of ‘dissipation’ or ‘damping’. Here we explain what these concepts mean, and why are they relevant.

< 6 min

How to measure crosslinking and collapse with QCM-D

Biocompatibility, antibacterial qualities, and drug delivery can be achieved by for example polymer brushes, polyelectrolyte multilayers or hydrogels. When tailoring the interfacial properties of these thin films, the layer conformation, such as crosslinking and degree of hydration is important.

~ 5 min

How to measure mass and thickness with QCM-D

Surface interaction processes and binding of molecules can be characterized by real-time nanoscale techniques, such as QCM-D, which measures mass and thickness.

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