Lipid-based systems are used in various fields of research, e.g. in the design and development of biosensor platforms, biomaterial coatings and drug delivery applications. In this overview, we present examples of how these lipid-based systems can be characterized using QSense QCM-D technology.
Polymer brushes, polyelectrolyte multilayers and hydrogels are typically used to achieve desirable properties. Key parameters influencing these properties are layer conformation and the degree of hydration. Here we show a straightforward way to measure polymer brush swelling and collapse.
Proteins tend to passively adsorb to surfaces. The amount adsorbed depends on many factors such as the protein itself, the ambient conditions and the surface material. So how can the adsorbed amount at these various conditions be assessed? Here we show how protein adsorption can be quickly measured.
In QCM instrument specifications and experimental descriptions, there is always a reference to the fundamental frequency. But does the fundamental frequency really matter? Here we sort out the details and explain how and why it matters in a measurement situation.
Quantifying QCM mass, there are two different approaches to choose from, the Sauerbrey equation or viscoelastic modeling. But what if the wrong method is applied, what happens then? How critical are the consequences? Here we describe what happens if the wrong quantification approach is used.
One of the key factors to achieve reliable and reproducible QCM measurements is temperature stability. Here we list the top four factors that will help you eliminate temperature induced artifacts in your QCM data.
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